Chromosomal Abnormalities

Expert Genetic Evaluation & Guidance for Healthy Parenthood

At Mediworld Fertility, Faridabad, we understand that infertility can have deeper, often hidden causes—including chromosomal abnormalities. These genetic issues may lead to infertility, recurrent miscarriages, or failed IVF cycles. Our fertility specialists and genetic counselors offer advanced testing and treatment options to help you build a healthy family with confidence and clarity.

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What Are Chromosomal Abnormalities?

Chromosomal abnormalities occur when there are missing, extra, or structurally altered chromosomes in the genetic material of one or both partners. These abnormalities can affect sperm or egg quality, embryo development, and successful pregnancy outcomes.

Humans typically have 46 chromosomes (23 pairs). An error in number or structure can cause:

• Infertility in men or women
• Recurrent pregnancy loss
• Birth defects or developmental delays
• Failed IVF or embryo implantation

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Common Chromosomal Abnormalities in Infertility

In Males

• Klinefelter Syndrome (XXY): Extra X chromosome; low testosterone, azoospermia or oligospermia
• Y Chromosome Microdeletions: Missing genetic material affecting sperm production
• Balanced Translocations: Parts of chromosomes swap positions, affecting sperm DNA

In Females

• Turner Syndrome (XO): Missing one X chromosome; leads to ovarian failure
• Mosaicism: Presence of both normal and abnormal cells
• Structural abnormalities: Inversions, deletions, or duplications of chromosome segments

In Embryos

• Aneuploidy: An abnormal number of chromosomes (e.g., Down syndrome – Trisomy 21)
• Embryo arrest due to genetic incompatibility

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How Chromosomal Issues Affect Fertility

• Poor embryo development
• Miscarriages after IVF or natural conception
• Implantation failure
• Low sperm count or non-motile sperm
• Early ovarian insufficiency in women
• Reduced IVF success rates

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Diagnosis at Mediworld Fertility

We offer advanced genetic and chromosomal testing such as:

• Karyotyping: Visual analysis of chromosomes from a blood sample
• FISH (Fluorescence In Situ Hybridization): Detects microdeletions in the Y chromosome
• PGT (Preimplantation Genetic Testing): Tests embryos during IVF for chromosomal integrity
• Genetic Counseling: Helps couples understand risks and treatment pathways

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Treatment Options for Chromosomal Abnormalities

For Men

• ICSI (Intracytoplasmic Sperm Injection): Helps fertilize the egg using even very few viable sperm
• Sperm Retrieval (TESA/TESE): When sperm are absent in ejaculate due to Y-chromosome microdeletion
• Donor Sperm (in severe or uncorrectable cases)

For Women

• Egg Donation: When chromosomal abnormality affects egg quality or ovarian reserve
• PGT-A or PGT-M Testing: To select genetically normal embryos before transfer
• IVF with Genetic Counseling: Personalized protocol based on risk profile

For Couples

• PGT with IVF: Improves implantation and reduces miscarriage risk
• Reproductive Genetics Counseling to explore safe conception options
• Embryo Freezing: When viable embryos are identified after genetic testing

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Why Choose Mediworld Fertility for Genetic Infertility Evaluation?

• In-House Genetic Counseling & Lab Partnerships
• Advanced IVF + PGT Services
• Experience with Complex Infertility Cases
• Ethical Guidance & Confidential Care
• Personalized Fertility Plans based on genetic profiles
• Supportive Counseling for emotional and medical needs

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Take Control with Knowledge-Driven Fertility Care

If you’ve experienced multiple failed IVF cycles, recurrent miscarriages, or unexplained infertility, genetic evaluation may offer the answers you need. At Mediworld Fertility, Faridabad, we provide comprehensive care that merges science, technology, and empathy—so you can move forward with confidence.

📞 Contact us: +91 9310751146
📧 Email us: info@mediworldfertility.com
📍 Address: SCO No. 84,85, Sector 16 Market, near Sagar Cinema, Faridabad, Haryana 121002, India