Immunological Screening

When the Body Fights Pregnancy – Discover Hidden Causes with Immunological Testing

At Mediworld Fertility, Faridabad, we offer Immunological Screening as part of our advanced fertility evaluation. Sometimes, the reason for infertility or repeated miscarriages lies not in the reproductive organs, but in the immune system. Abnormal immune responses may cause the body to reject the embryo, interfere with implantation, or attack reproductive cells. Our screening helps detect these issues early and guides effective treatment.

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What is Immunological Infertility?

Immunological infertility occurs when the immune system mistakenly identifies sperm, eggs, or embryos as foreign invaders and responds by attacking or rejecting them. This can prevent conception or lead to repeated pregnancy losses.

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Who Should Consider Immunological Screening?

Immunological tests are recommended for:

• Couples with unexplained infertility
• Women with recurrent miscarriages (2 or more)
• Repeated IVF or IUI failures despite good embryo quality
• Autoimmune conditions (e.g., lupus, rheumatoid arthritis, thyroiditis)
• History of antiphospholipid syndrome or thrombophilia
• Women with positive ANA or elevated NK cells

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Key Immunological Tests at Mediworld Fertility

1. Antiphospholipid Antibody Panel (APLA)
   Detects clot-forming antibodies that can cause miscarriages or poor implantation.
2. Lupus Anticoagulant Test
   Identifies a specific autoimmune factor that increases clotting risk.
3. Antinuclear Antibody (ANA) Test
   Screens for systemic autoimmune disorders that can affect pregnancy.
4. Thyroid Antibodies (TPO, TG-Ab)
   Checks for autoimmune thyroiditis, which impacts fertility and pregnancy outcomes.
5. Natural Killer (NK) Cell Activity
   Elevated NK cells may damage the embryo or prevent implantation.
6. HLA Matching & DQ Alpha Testing
   Assesses genetic compatibility and immune tolerance between partners.
7. Anti-Sperm Antibodies (ASA)
   Found in men or women; these antibodies may attack sperm, reducing motility and function.

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Why Immunological Issues Matter in Fertility

• Interfere with sperm transport or egg fertilization
• Prevent implantation of healthy embryos
• Trigger early pregnancy loss due to immune rejection
• Cause poor response to IVF or repeated embryo transfer failure

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Treatment Options After Abnormal Results

At Mediworld Fertility, treatment is personalized and may include:

• Low-dose corticosteroids (to reduce immune overactivity)
• Low Molecular Weight Heparin (LMWH) and aspirin for clotting disorders
• IVIG or Intralipid therapy for immune modulation in IVF cycles
• Thyroid management for autoimmune thyroid dysfunction
• Plasmapheresis in select cases with severe immune reaction
• Lifestyle and nutritional modifications to support immune balance

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Why Choose Mediworld Fertility for Immunological Screening in Faridabad?

• Expert Reproductive Immunology Panel
• Accurate In-House & Partner Lab Testing
• Specialized IVF Protocols for Immune-Related Cases
• Ethical, Evidence-Based Treatment Plans
• Complete Fertility & Autoimmune Integration
• Affordable Packages and Transparent Communication

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Unexplained Infertility Has an Explanation — Let’s Find It Together

If you’ve faced failed IVF cycles, recurrent pregnancy loss, or unexplained infertility, immunological screening could provide the missing piece. At Mediworld Fertility, Faridabad, we combine scientific precision with empathetic care to help you take the next step toward a healthy pregnancy.

📞 Contact us: +91 9310751146
📧 Email us: info@mediworldfertility.com
📍 Address: SCO No. 84,85, Sector 16 Market, near Sagar Cinema, Faridabad, Haryana 121002, India